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Nystagmus

Pronounced: ni-STAG-mus

Definition

Nystagmus is a type of involuntary movement of the eyes. It is usually side-to-side (horizontal nystagmus) , but sometimes is up and down (vertical nystagmus) or in a circular fashion (rotatory nystagmus). The movement varies between slow and fast and usually involves both eyes. In infancy, it tends to develop between six weeks and three months of age and is called infantile nystagmus. It can also be acquired later in life and is called acquired nystagmus.

Causes

The direct cause of nystagmus is instability in the motor system that controls the eyes. In some cases, the cause of nystagmus is unknown.

Risk Factors

There are a number of factors or conditions that increase the risk of this instability, including:

  • Genetics
  • A family member with nystagmus
  • Poor development of eye control that may be caused by an eye disease or visual problem during infancy, such as bilateral optic nerve hypoplasia or congenital cataracts
  • Albinism—lack of skin pigmentation
  • Eye disorders, such as optic nerve degeneration or severe astigmatism or severe nearsightedness
  • Diseases of the body, such as Meniere’s disease which involves balance problems, multiple sclerosis, spasmus nutans, or stroke
  • Injury to the head or involving the body’s motor system
  • Use of certain medications, such as lithium or antiseizure medications
  • Alcohol abuse or drug use
  • Inner ear problems, such as infections, irritation, benign paroxysmal positional vertigo, some brain tumors
  • Thiamine or vitamin B12 deficiency
  • Any disease that can also affect the brain
Symptoms

Other symptoms besides the eye movements may include:

  • Sensitivity to light
  • Difficulty seeing in darkness
  • Vision problems
  • Head held in a turned position
  • Oscillopsia—feeling that the world is shaking or moving
  • Vertigo
Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done. If nystagmus seems to be present, you may need:

  • A full exam with an eye specialist called an ophthalmologist
  • An ear exam, including a hearing test
  • Exam with a neurologist or other medical specialist

Tests may include the following:

Magnetic Resonance Imaging

MRI of the Brain

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The ophthalmologist will also look for other eye problems that may be related to the nystagmus, such as strabismus, cataracts , or abnormality of the optic nerves or retina.

The ear specialist will look for signs of ear infection, and for worsening of the nystagmus with head positions.

Treatment

Talk with your doctor about the best treatment plan for you. Removal of the cause of nystagmus can sometimes eliminate the problem, for example discontinuing a medication or stopping alcohol or drug use. However, nystagmus often is a permanent condition that can only be reduced and not eliminated. Treatment options to reduce nystagmus and improve vision include the following:

  • Prisms, tints, eyeglasses, or contact lenses
  • Adopting a particular angle of vision where the nystagmus is reduced, such as holding the head in a certain position
  • Vibratory stimulation of the face and neck
  • Certain medications for certain types of nystagmus, including botox (botulinum toxin) injections to relax the eye muscles, muscle relaxants, and certain anti-seizure medications
  • Surgery on the eye muscles

Low-vision aids can often help improve vision. They may include large print or high contrast materials, good lighting, and magnifying devices.

Prevention

There is no known way to prevent nystagmus.

RESOURCES:

American Academy of Ophthalmology
http://www.aao.org

American Nystagmus Network
http://www.nystagmus.org

CANADIAN RESOURCES:

The Canadian Association of Optometrists
http://www.opto.ca

Canadian Ophthalmological Society
http://www.eyesite.ca

References:

Eye facts about nystagmus. American Nystagmus Network website. Available at: http://www.nystagmus.org/aao.html. Accessed February 18, 2013.

General information about nystagmus. American Nystagmus Network website. Available at: http://www.nystagmus.org/aboutn.html. Accessed February 18, 2013.

Hertle RW. Understanding and treatment of infantile nystagmus syndrome. Presentation at the 4th Biennial Conference of the American Nystagmus Network, Los Angeles, CA. July 8-10, 2005. American Nystagmus Network website. Available at: http://www.nystagmus.org/doc/conf2005/hertle_ANN.pdf. Accessed February 18, 2013.

Nystagmus. American Academy of Ophthalmology eyeSmart website. Available at: http://www.geteyesmart.org/eyesmart/diseases/nystagmus.cfm. Accessed February 18, 2013.

Maybodi M. Understanding nystagmus: diagnosis, related disorders, treatment, and research. Presentation at the 3rd Biennial Conference of the American Nystagmus Network, Baltimore, MD. July 11-13, 2003. Available at: http://www.nystagmus.org/doc/conf2003/KEYNOTE.pdf. Accessed February 18, 2013.



Last reviewed March 2013 by Michael Woods, MD

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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