Nonsteroidal anti-inflammatory drugs (NSAIDs) have received press in the past for their association with dangerous side effects among older adults compared to younger people. Many older people take NSAIDs to get relief from pain, stiffness, and inflammation. However, these medications can have side effects. If you are taking NSAIDs, check the US Food and Drug Administration's (FDA) website medication guide for more information.
Gastrointestinal problems, including stomach pain, ulcers, and bleeding of the stomach lining, are potential side effects among people who take NSAIDs on a regular basis. Often, the first indication of gastrointestinal damage in seniors is bleeding. There can also be warning symptoms of nausea, abdominal pain, diarrhea, or dyspepsia (indigestion and gas).
NSAIDs may create or worsen gastroesophageal reflux disease (GERD), which is a disorder that results in food and stomach acid backing up into the esophagus from the stomach. Symptoms and complications may include:
The American College of Gastroenterology lists the following as key issues that may put a person taking NSAIDs at risk for GI problems:
If any of the following warning signs appear, contact your physician right away:
Several studies found that problems with NSAIDs are not just stomach-related. Regular use of NSAIDs may lead to:
People at older ages usually need more medications. Unfortunately, NSAIDs can interfere with common medications that they take, such as blood thinners, blood pressure medication, and and diuretics.
Drug doses for seniors are typically lower than those recommended for younger people due to these changes in the body as people age:
Alliance for Aging Research
The College of Family Physicians of Canada
Public Health Agency of Canada
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Last reviewed April 2017 by Michael Woods, MD, FAAP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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