Main Page | Risk Factors | Reducing Your Risk | Screening | Symptoms | Diagnosis | Treatment Overview | Chemotherapy | Radiation Therapy | Surgical Procedures | Lifestyle Changes | Talking to Your Doctor | Resource Guide
If esophageal cancer is localized and has not spread beyond the original site, surgical removal of the cancer is the most common treatment. The goal is to remove as much of the cancer as possible while preserving as much function of the esophagus as possible. It may also be done with chemoradiation, a combination of radiation therapy and chemotherapy to shrink the tumor before surgery or to try to kill off any remaining cancer cells after surgery. Surgical removal is not always an option since most esophageal cancers are found in advanced stages. In this case, surgery may be done as palliative care to improve the function of the esophagus.
Esophageal surgeries are long and difficult procedures that often have postoperative complications. It is important to seek out an experienced surgeon and hospital for these procedures.
Depression is a common symptom of esophageal cancer. During a hospital stay, psychotherapy may be part of the treatment plan.
High grade dysplasia is a change in cell structure that is a precursor to cancer. Surgery for high grade dysplasia and early stage cancer offer the best chance for a cure. Options include:
Small, noninvasive cancer can be removed during an endoscopy. A tube with a lighted tip and camera is inserted through the mouth and throat. It can also be inserted through small incisions in chest and/or abdomen if the surgeon needs to access the tumor from a different angle. The tumor is removed along with a margin of healthy tissue to try to ensure that all the cancer is completely removed. The doctor will examine and take samples of the removed tissue. Tissue samples will be examined under a microscope for the presence of cancer.
Photosensitizers, or light-sensitive molecules, are injected into the bloodstream. These molecules are absorbed by cells throughout the body, but tend to remain longest in cancer cells. When these molecules are exposed to a special red light, they cause cell damage and death. The light will be directed to the tumor using an endoscope.
An esophagectomy is the removal of part or all of the esophagus. The amount of tissue removed depends on the location and size of the tumor. In some cases, the stomach is stretched up into the chest and neck, and attached to the remaining part of the esophagus. If large amounts of tissue are removed, a plastic tube or intestinal tissue may be used to create a connection between the mouth and the stomach.
Nearby lymph nodes may also be removed and tested for the presence of cancer. Cancer in the lymph nodes means the cancer may have spread to other areas of the body.
Esophagectomies can be done as:
A feeding tube can be inserted through the abdominal wall and directly into the stomach or small intestine. This is done when swallowing becomes difficult and nutritional needs are not able to be met. Nutritional support helps prevent starvation, as well as aspiration of material into the lungs.
The feeding tube can be placed as part of a scheduled surgery or done separately. The opening through the abdomen is called a stoma. The rubber tube from the stoma is fixed and secure. Complete, balanced liquid meals and medications can be delivered through the tube.
If a surgical cure is not an option, there are a few options available to help keep the esophageal channel open as long as possible. All of these procedures are done during an endoscopy.
ASGE Technology Committee, Kantsevoy SV, Adler DG, et al. Endoscopic mucosal resection and endoscopic submucosal dissection. Gastrointest Endosc. 2008;68(1):11-18.
Esophageal and esophagogastric junction cancer. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114816/Esophageal-and-esophagogastric-junction-cancer. Updated January 18, 2016. Accessed January 3, 2017.
Esophageal cancer. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal-disorders/tumors-of-the-gi-tract/esophageal-cancer. Updated July 2014. Accessed January 3, 2017.
Esophagus cancer. American Cancer Society website. Available at http://www.cancer.org/acs/groups/cid/documents/webcontent/003098-pdf.pdf. Accessed January 3, 2017.
Kato H, Nakajima M. Treatments for esophageal cancer: a review. Gen Thorac Cardiovasc Surg. 2013;61(6):330-335.
Lightdale CJ. Endoscopic treatments for early esophageal cancer. Gastroenterol Hepatol (NY). 2007;3(12):904-906.
Mackenzie DJ, Popplewell PK, Billingsley KG. Care of patients after esophagectomy. Crit Care Nurse. 2004;24(1):16-29.
Nakajima M, Kato H. Treatment options for esophageal squamous cell carcinoma. Expert Opin Pharmacother. 2013;14(10):1345-1354.
Treatment option overview. National Cancer Institute website. Available at: https://www.cancer.gov/types/esophageal/patient/esophageal-treatment-pdq#section/_159. Updated July 19, 2016. Accessed January 3, 2017.
Vignesh S, Hoffe SE, Meredith KL, et al. Endoscopic therapy of neoplasia related to Barrett's esophagus and endoscopic palliation of esophageal cancer. Cancer Control. 2013;20(2):117-129.
9/18/2007 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T116155/Gastric-carcinoma: Küchler T, Bestmann B, Rappat S, Henne-Bruns D, Wood-Dauphinee S. Impact of psychotherapeutic support for patients with gastrointestinal cancer undergoing surgery: 10-year survival results of a randomized trial. J Clin Oncol. 2007;25(19):2702-2708.
Last reviewed December 2016 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2012 EBSCO Publishing All rights reserved.
What can we help you find?close ×